Exmere

    Silica family

    Exsil 100

    The original Exsil range – 100 Å Type A silica with the widest choice of bonded phases.

    100 Å208 m²/g3 – 15 µmType A
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    Exsil 100

    Pore size

    100 Å (± 3 Å)

    Surface area

    208 m²/g

    Pore volume

    0.52 mL/g

    Particle sizes

    3 – 15 µm

    Silica type

    Type A

    Bonded phases

    17

    What is Exsil 100

    Exsil 100

    Exsil 100 is the original Exsil range, developed as an alternative to Spherisorb-type products. It is a Type A silica with a 100 Å pore diameter controlled to ± 3 Å, a pore volume of 0.52 mL/g and a surface area of 208 m²/g.

    Its extensive range of bonded phases includes the base-deactivated ODS-B and Octyl-B phases, which are so deactivated that they can chromatograph strong bases in buffer-free eluents.

    Why Exsil 100

    Why chromatographers choose Exsil 100.

    Widest range of bonded phases

    17 chemistries from C1 to SAX and SCX, including Diol and Phenyl-HL.

    Tight pore control

    100 Å media is typically controlled between 97 and 103 Å with a pore volume of 0.50 – 0.52 mL/g.

    Base-deactivated ODS-B and Octyl-B

    Among the first base-deactivated analytical reversed phases, allowing many bases to be run without buffers.

    Proven in the literature

    Exsil 100 columns have been used in peer-reviewed methods since 1990.

    Typical applications

    Where Exsil 100 is used.

    Collagen cross-links

    Ion-pair reversed-phase assay – James, Perrett & Thompson, J. Chromatogr. B 525 (1990) 43.

    Natural products

    Profiling on Exsil 100-5 ODS – Wongsawatkul et al., Int. J. Mol. Sci. 9 (2008) 2724.

    Oligosaccharides

    Separation on Exsil 100 HAAX, 1.5 µm – Li et al., J. Food Compos. Anal. (2026).

    Electrochromatography

    Sulfonated Exsil 100 as packing material – Pirogov & Buchberger, J. Chromatogr. A 916 (2001) 51.

    Performance evidence

    Performance evidence

    Batch-to-batch consistency

    50 production batches of Exsil 100 silica: pore diameter 91 – 103 Å, pore volume 0.51 – 0.54 mL/g, surface area 201 – 224 m²/g.

    Example quality assurance report

    Batch 22/411, 5 µm: median pore diameter 100 Å, pore volume 0.52 mL/g, surface area 207 m²/g, mean diameter 5.00 µm (number), SD 0.88 µm.

    Technical characteristics

    Engineered properties.

    Particle sizes3, 5, 7, 10, 12, 15 µm
    Pore size100 Å (± 3 Å)
    Specific surface area208 m²/g
    Pore volume0.52 mL/g
    Silica typeType A
    Base silicaExsil 100
    Carbon loadC1 3 %, C8 6 %, ODS 11 %, ODS-1 7 %, ODS-B 12 %, CN 3.5 %, NH₂ 2 %, SAX 3 %, SCX 3 %
    MorphologySpherical, porous

    Available modifications

    Bonded phases on Exsil 100.

    Reversed phase

    • ODS (C18, endcapped) · L1
    • ODS-1 (C18, not endcapped) · L1
    • ODS-B · L1
    • ODS-AB · L1
    • Octyl C8 (endcapped) · L7
    • Octyl-B · L7
    • Octyl-AB · L7
    • Hexyl C6 · L15
    • TMS C1 · L13
    • Phenyl-HL · L11

    Normal phase / HILIC

    • Silica · L3
    • Amino NH₂ · L8
    • Nitrile CN · L10
    • Nitrile HL · L10
    • Diol · L20

    Ion exchange

    • SAX · L14
    • SCX · L9
    Explore full bonded-phase portfolio

    Sizes & formats

    Sizes & formats

    Particle sizeScale
    3 µmHigh-throughput analytical
    5 µmRoutine HPLC / QC
    7 µmSemi-preparative
    10 µmPreparative
    12 / 15 µmPreparative / process

    FAQ

    Frequently asked questions.

    Next step

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