Exmere

    Classical HPLC silica

    Exsil Avanti

    Reliable classical HPLC silica for established analytical methods.

    Exsil Avanti is designed for laboratories relying on proven analytical HPLC methods. Manufactured with physical silica characteristics comparable to classical Hypersil® silica, it delivers familiar chromatographic behaviour together with dependable long-term availability.

    130 Å200 m²/g1.5 µm – 10 µmClassical Type A
    Request a sample See full specification
    Exsil Avanti spherical silica microspheres
    Fully spherical · 130 Å · 1.5 – 10 µm

    Pore size

    130 Å

    Surface area

    200 m²/g

    Morphology

    Fully spherical

    Particle sizes

    1.5 µm – 10 µm

    Silica type

    Classical Type A

    pH range

    2 – 8

    What is Exsil Avanti

    Classical spherical silica for established analytical HPLC methods.

    Exsil Avanti is a fully spherical HPLC silica with 130 Å pore diameter and 200 m²/g specific surface area. It is manufactured with physical characteristics comparable to classical Hypersil® silica, making it a dependable option for laboratories that rely on validated legacy methods.

    The full bonded-phase portfolio — reversed-phase, normal-phase and ion-exchange — is available across 1.5 µm to 10 µm from a single silica lineage, so methods scale predictably from UHPLC screening through routine QC to preparative isolation.

    Why Exsil Avanti

    Why chromatographers choose Exsil Avanti.

    Built around proven chromatography

    Designed for laboratories using well-established analytical HPLC methods.

    Comparable physical silica

    Manufactured with physical silica characteristics comparable to classical Hypersil® silica.

    Complete bonded-phase portfolio

    Available in reversed-phase, normal-phase and ion-exchange chemistries.

    Reliable long-term supply

    Consistent UK manufacturing for laboratories requiring dependable long-term availability.

    Where it fits

    Applications.

    Applications

    Coming soon

    Representative application examples and chromatographic methods for Exsil Avanti are currently being prepared and will be added soon.

    Request an application note

    Performance evidence

    Performance evidence

    Comparison chromatograms and batch-to-batch physical-property data. Full application notes and raw data available on request.

    Application note

    Coming soon

    Comparison chromatograms

    Comparison chromatograms demonstrating chromatographic behaviour will be added soon.

    Batch-to-batch consistency of Exsil Avanti surface area, pore volume and pore diameter across nine production batches

    Quality data

    Batch-to-batch consistency

    Nine consecutive Exsil Avanti production batches demonstrating excellent batch-to-batch consistency in surface area (~200 m²/g), pore volume (~0.51 mL/g) and pore diameter (~130 Å) — providing the reproducible silica morphology required for consistent column performance.

    Full specification

    Engineered properties.

    Mean particle size1.5 µm, 3 µm, 5 µm, 10 µm
    Pore size130 Å
    Specific surface area200 m²/g
    MorphologyFully spherical
    pH operating range2 – 8
    Silica typeClassical Type A

    Full Certificate of Analysis and detailed characterisation data (BET, mercury porosimetry, ICP-MS trace metals, PSD) available on request.

    Bonded phases

    Available Exsil Avanti chemistries.

    Reversed-phase, normal-phase and ion-exchange chemistries — each supplied with its USP L-classification.

    Reversed Phase

    • ODS
      USP L1
    • C8 (1)
      USP L7
    • C8 (2)
      USP L7
    • C1 (TMS)
      USP L13

    Normal Phase

    • Silica
      USP L3
    • NH₂ (2)
      USP L8
    • CN (1)
      USP L10
    • Phenyl
      USP L11

    Ion Exchange

    • SAX
      USP L14
    • SCX
      USP L9
    Explore full bonded-phase portfolio

    Sizes & formats

    From UHPLC to process scale.

    Particle sizeTypical useAvailability
    1.5 µmUHPLC — fast analytical
    Analytical
    3 µmHigh-throughput analytical
    Analytical
    5 µmRoutine HPLC / QC workhorse
    Analytical + semi-prep
    10 µmPreparative / process scale
    Preparative & bulk

    Scale-up

    Same silica, every scale.

    1.5 µm

    UHPLC screen

    3 – 5 µm

    Analytical method

    10 µm

    Semi-prep

    10 µm bulk

    Process scale

    Because every particle size shares the same base silica synthesis and bonding process, selectivity and retention translate predictably across scales — no re-development when moving from method screening to production.

    Why buy from Exmere

    A silica manufacturer that does not compete with its customers.

    Bulk silica specialist

    40+ years of manufacturing HPLC silica in the UK. We supply the bulk material — you own the finished product.

    OEM neutral

    Column-packing customers can specify Exsil Avanti without competitive risk.

    Analytical to process scale

    The same silica lineage from R&D samples through to hundreds of kilos — no supplier changes as you scale.

    FAQ

    Frequently asked questions.

    Next step

    Talk to us about Exsil Avanti.

    Request a technical sample, a full CoA, or a quotation for bulk supply. A chromatography specialist will respond within one business day.

    Free technical evaluation samples

    Full CoA and characterisation data

    OEM & private-label supply

    Response within one business day

    Exmere Ltd — HPLC Silica Engineering

    Unit 8, Boundary Way, Kellet Road Industrial Estate, Carnforth, Lancashire LA5 9XP, UK

    info@exmere.eu · +44 (0)1524 734451