Exmere

    Type B silica

    Exsil Plus

    Acid, base and chelate deactivated Type B silica – uncapped for a selectivity different from standard BDS media.

    100 Å / 300 Å210 m²/g1.5 – 10 µmType B
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    Exsil Plus

    Exsil Plus C18 EPS is also sold as Exsil Diametric C18 – same phase, two names.

    View Exsil Diametric C18

    Pore size

    100 Å / 300 Å

    Surface area

    210 / 100 m²/g

    Pore volume

    0.52 / 0.78 mL/g

    Particle sizes

    1.5 – 10 µm

    Silica type

    Type B

    Bonded phases

    9

    What is Exsil Plus

    Exsil Plus

    Exsil Plus is the Type B version of Exsil 100 and Exsil 300: acid, base and chelate deactivated and left uncapped, giving a different selectivity from standard BDS media.

    It is available as 100 Å silica (0.52 mL/g, 210 m²/g) and 300 Å silica (0.78 mL/g, 100 m²/g). The Exsil Plus C18 EPS phase is also offered under the name Exsil Diametric C18.

    Why Exsil Plus

    Why chromatographers choose Exsil Plus.

    Different selectivity

    Exsil Plus C18 shows a far higher silanol activity relative to hydrophobicity than Symmetry, Inertsil or Kromasil C18 (α amitriptyline/phenylvaleric acid ≈ 2 vs. below 0.5).

    Controlled phase loading

    C18 EPS bonded at defined levels from 0.25 to 2.6 µmol/m².

    Deactivated for bases and chelates

    Acid, base and chelate deactivation gives good peak shape with bases despite the alternative selectivity.

    Typical applications

    Where Exsil Plus is used.

    Acids and bases

    Exsil Plus 100/5 ODS vs. Exsil 100/5 ODS, 150 × 4.6 mm, 50 % MeCN / 0.05 M KH₂PO₄ pH 3.

    Selectivity tuning

    Bonding-level series on Exsil Plus C18 EPS 5 µm, 100 × 4.6 mm: cinnamic acid, nitrobenzene, toluene, amitriptyline, biphenyl.

    Published

    Exsil Plus EPS C18 5 µm – Huo et al., J. Adv. Res. 24 (2020) 325.

    Performance evidence

    Performance evidence

    Quality assurance – C18-PFP

    Exsil Plus 100 C18-PFP, lot 180430: pore volume 0.52 mL/g, surface area 210 m²/g, carbon content 8 %.

    Quality assurance – C2

    Exsil Plus 100 C2, lot 180515: pore volume 0.52 mL/g, surface area 210 m²/g, carbon content 5 %.

    Technical characteristics

    Engineered properties.

    Particle sizes1.5, 3, 5, 7, 10 µm
    Pore size100 Å / 300 Å
    Specific surface area210 m²/g (100 Å) / 100 m²/g (300 Å)
    Pore volume0.52 mL/g (100 Å) / 0.78 mL/g (300 Å)
    Silica typeType B, acid/base/chelate deactivated
    Base silicaExsil 100 / Exsil 300
    Carbon loadC18-PFP 8 %, C2 5 %; others available on request
    MorphologyAvailable on request

    Available modifications

    Bonded phases on Exsil Plus.

    Reversed phase

    • ODS (C18) · L1
    • C18 EPS (= Exsil Diametric C18) · L1
    • C18-PFP
    • C8 · L7
    • C8-EPS · L7
    • C2

    Normal phase

    • Silica · L3
    • CN · L10
    • NH₂ · L8
    Explore full bonded-phase portfolio

    Sizes & formats

    Sizes & formats

    Particle sizeScale
    1.5 µmUHPLC – fast analytical
    3 µmHigh-throughput analytical
    5 µmRoutine HPLC / QC
    7 µmSemi-preparative
    10 µmPreparative

    FAQ

    Frequently asked questions.

    Next step

    Exsil Plus enquiry

    Request quotation Contact technical support